Product Description:
Ivermectin is a macrocyclic lactone derived from avermectin, used as an antiparasitic agent.
Applications & Uses:
CAS#:
70288-86-7
SYNONYM:
22,23-Dihydroavermectin B1;Ivermectin B1a;Ivermectin B1b
FORMULA:
C48H74O14
PRODUCT TYPE:
HAZARD:
Irritant
CATEGORIES:
Pharmaceutical
,
Animal Health
,
Organics
Ivermectin is a potent, broad-spectrum antiparasitic agent renowned for its efficacy across a range of parasitic infections. Comprising two structurally related macrocyclic lactone compounds, Ivermectin''s chemical structure allows it to bind with high affinity to glutamate-gated chloride ion channels, which are vital to the neuromuscular function of parasites. This interaction results in increased permeability of the cell membrane to chloride ions, ultimately leading to paralysis and death of the parasite. Primarily used in veterinary medicine and human healthcare, it effectively combats a variety of conditions caused by nematode and arthropod infestations. In animals, it is used for the prevention and treatment of heartworm and acariasis among other parasitic infections. Additionally, Ivermectin is a crucial treatment component in combating river blindness (onchocerciasis) and lymphatic filariasis in humans, making it an essential pharmaceutical in both tropical regions and developed countries. Its safety profile and versatility affirm Ivermectin''s status as a critical tool in parasitic disease management.