Gefitinib Supplier & Distributor of CAS# 184475-35-2

Gefitinib

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Product Description:

Gefitinib is an anilinoquinazoline used for the treatment of non-small cell lung cancer.

Applications & Uses:

CAS#:

184475-35-2

SYNONYM:

ZD1839;Iressa;Gefitinibum

FORMULA:

C22H24ClFN4O3

PRODUCT TYPE:

HAZARD:

Warning

CATEGORIES:

Pharmaceutical

Technical Specifications

Appearance :

White to pale yellow powder

Melting point, °C :

201-203

Molecular weight, g/mol :

446.9

Gefitinib is a potent, selective inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase, a key enzyme involved in the regulation of crucial cellular processes such as proliferation, survival, and differentiation. Designed to specifically target and bind to the ATP-binding site of the enzyme, gefitinib effectively disrupts aberrant signaling pathways that are often associated with the pathogenesis of various cancers. As a quinazoline derivative, gefitinib''s molecular design enhances its specificity and efficacy in impeding tumor growth predominantly in non-small cell lung cancer (NSCLC), particularly those exhibiting somatic mutations within the EGFR gene. Its oral bioavailability ensures convenient administration, making it an essential treatment option as a first-line therapy or in settings where previous treatments have failed, thereby offering hope for improved patient outcomes in oncological care.

Details

CAS #

184475-35-2

CATEGORIES:

Pharmaceutical

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