Amsacrine hydrochloride Supplier & Distributor of CAS# 7720-71-8

Amsacrine hydrochloride

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Product Description:

Amsacrine hydrochloride is an antineoplastic agent used in cancer chemotherapy.

Applications & Uses:

CAS#:

7720-71-8

SYNONYM:

m-AMSA;Amsidine;4'-[4-(3-Amino-5-methoxycarbonylphenylsulfamoyl)anilino]methanesulfonanilide hydrochloride

FORMULA:

C21H20ClN3O3S

PRODUCT TYPE:

HAZARD:

Toxic

CATEGORIES:

Pharmaceutical

Technical Specifications

Appearance :

yellow powder

Melting point, °C :

223-225

Molecular weight, g/mol :

435.85

Amsacrine hydrochloride is a potent antitumor agent known for its effectiveness in treating certain types of cancer. This compound features a chemically sophisticated structure, comprising a naphthoquinone moiety linked to an acridine group, which facilitates its interaction with DNA. Acting primarily as an intercalating agent, Amsacrine hydrochloride inserts itself between DNA base pairs, disrupting the critical processes of replication and transcription which are necessary for cancer cell proliferation. This mechanism of action makes it particularly valuable in the treatment of acute lymphoblastic leukemia and other hematologic malignancies. The hydrochloride salt form enhances its solubility and stability, enabling optimized delivery in therapeutic applications. Amsacrine hydrochloride is a vital tool in oncology research and cancer therapy, providing substantial benefits in clinical settings due to its targeted approach in disrupting cancer cell growth.

Details

CAS #

7720-71-8

CATEGORIES:

Pharmaceutical

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