Product Description:
ANA-12 is a selective antagonist of tropomyosin receptor kinase B (TrkB), often used in research on neurobiology and neuropharmacology.
Applications & Uses:
CAS#:
383565-92-2
SYNONYM:
ANA12;Triazolo[1,5-a]pyrimidine derivative
FORMULA:
C13H9ClN4OS
PRODUCT TYPE:
HAZARD:
Hazardous
CATEGORIES:
Pharmaceutical
,
Specialty Chemicals
,
Research and Development
Technical Specifications
ANA-12 is a selective and potent small-molecule antagonist of the TrkB receptor, known for its distinct role in inhibiting the tropomyosin receptor kinase B (TrkB)-related pathways. With its unique chemical structure, ANA-12 exhibits high affinity and specificity, making it an invaluable tool for scientific research and drug development.
Primarily used in neuroscience research, ANA-12 aids in understanding the mechanisms that underpin neurodegenerative diseases, neural development, and synaptic plasticity. It effectively disrupts TrkB signaling without affecting TrkA or TrkC, allowing researchers to delve into the specific pathways influenced by brain-derived neurotrophic factor (BDNF)-TrkB interactions.
Furthermore, ANA-12 holds promise in various therapeutic applications, including its contribution to studies exploring treatments for conditions such as Alzheimer''s disease, depression, and other TrkB-dependent disorders. Its well-documented role in reducing the downstream effects of TrkB activation makes ANA-12 a critical component in preclinical studies aimed at elucidating new therapeutic avenues for neuropsychiatric and neurodegenerative conditions.
As a high-quality research-grade compound, ANA-12 offers reliable performance and reproducibility, ensuring consistent results across a wide array of experimental settings.